Publication
Model-based neuroanatomy: Tractography validation, white-matter connections and geometrical organization
Abstract
Diffusion-weighted MRI (DWI) coupled with fiber tractography allows for non-invasive measurement of the organization of white-matter fascicles in the living human brain. Investigators can choose between many possible DWI measurements and tractography algorithms to estimate a full set of white-matter fascicles; the connectome. Each algorithm, creates connectomes based on different principles, such differences make connectome measurements dependent not only on the brain biology but also on tractography (e.g., Fig 1A; Fascicles identified with two different tractography algorithms). Hereafter, we propose a method for validating connectomes based on both their geometric consistency and their quality in predicting the diffusion signal. We apply this method to study the geometric structure of white-matter fibers.
Download publicationRelated Resources
See what’s new.
2009
A Multi-cellular Developmental Representation for Evolution of Adaptive Spiking Neural Microcircuits in an FPGAIt has been shown that evolutionary and developmental processes can be…
2002
Why Distance Matters: Effects on Cooperation, Persuasion and DeceptionIn this study, we examine how geographic distance affects…
2018
Dream Lens: Exploration and Visualization of Large-Scale Generative Design DatasetsThis paper presents Dream Lens, an interactive visual analysis tool…
2009
Multiscale 3D Reference VisualizationReference grids are commonly used in design software to help users…
Get in touch
Something pique your interest? Get in touch if you’d like to learn more about Autodesk Research, our projects, people, and potential collaboration opportunities.
Contact us